Molecular architecture of the ErbB2 extracellular domain homodimer

Human epidermal growth factor receptors (HERs or ErbBs) play crucial roles in numerous cellular processes. ErbB2 is a key member of ErbB family, and its overexpression is recognized as a frequent molecular abnormality. In cancer, this overexpression correlates with aggressive disease and poor patien...

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Veröffentlicht in:Oncotarget
Hauptverfasser: Hu, Shi, Sun, Yuna, Meng, Yanchun, Wang, Xiaoze, Yang, Weili, Fu, Wenyan, Guo, Huaizu, Qian, Weizhu, Hou, Sheng, Li, Bohua, Rao, Zihe, Lou, Zhiyong, Guo, Yajun
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals LLC 2015
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4359325/
https://ncbi.nlm.nih.gov/pubmed/25633808
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