Cancer exosomes trigger mesenchymal stem cell differentiation into pro-angiogenic and pro-invasive myofibroblasts

Stromal fibroblasts become altered in response to solid cancers, to exhibit myofibroblastic characteristics, with disease promoting influence. Infiltrating mesenchymal stem cells (MSC) may contribute towards these changes, but the factors secreted by cancer cells that impact MSC differentiation are...

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Vydáno v:Oncotarget
Hlavní autoři: Chowdhury, Ridwana, Webber, Jason P., Gurney, Mark, Mason, Malcolm D., Tabi, Zsuzsanna, Clayton, Aled
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals LLC 2014
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4359250/
https://ncbi.nlm.nih.gov/pubmed/25596732
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