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Tumor stroma-derived factors skew monocyte to dendritic cell differentiation toward a suppressive CD14(+) PD-L1(+) phenotype in prostate cancer

Tumor-associated stromal myofibroblasts are essential for the progression and metastatic spread of solid tumors. Corresponding myeloid cell infiltration into primary tumors is a negative prognostic factor in some malignancies. The aim of this study was to define the exact role of stromal myofibrobla...

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Detalhes bibliográficos
Publicado no:Oncoimmunology
Main Authors: Spary, Lisa K, Salimu, Josephine, Webber, Jason P, Clayton, Aled, Mason, Malcolm D, Tabi, Zsuzsanna
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4292218/
https://ncbi.nlm.nih.gov/pubmed/25941611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/21624011.2014.955331
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