Cancer exosomes trigger mesenchymal stem cell differentiation into pro-angiogenic and pro-invasive myofibroblasts

Stromal fibroblasts become altered in response to solid cancers, to exhibit myofibroblastic characteristics, with disease promoting influence. Infiltrating mesenchymal stem cells (MSC) may contribute towards these changes, but the factors secreted by cancer cells that impact MSC differentiation are...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Chowdhury, Ridwana, Webber, Jason P., Gurney, Mark, Mason, Malcolm D., Tabi, Zsuzsanna, Clayton, Aled
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2014
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4359250/
https://ncbi.nlm.nih.gov/pubmed/25596732
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