Intrinsic TGF-β2-triggered SDF-1-CXCR4 signaling axis is crucial for drug resistance and a slow-cycling state in bone marrow-disseminated tumor cells

Dormant or slow-cycling disseminated tumor cells (DTCs) in bone marrow (BM) are resistant to conventional therapy in various cancers including head and neck squamous cell carcinoma (HNSCC), although the molecular mechanisms remain largely unknown. This study aimed to identify the intrinsic molecular...

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Podrobná bibliografie
Vydáno v:Oncotarget
Hlavní autoři: Nakamura, Takuya, Shinriki, Satoru, Jono, Hirofumi, Guo, Jianying, Ueda, Mitsuharu, Hayashi, Mitsuhiro, Yamashita, Satoshi, Zijlstra, Andries, Nakayama, Hideki, Hiraki, Akimitsu, Shinohara, Masanori, Ando, Yukio
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals LLC 2014
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4359213/
https://ncbi.nlm.nih.gov/pubmed/25504440
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