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HP1β Is a Biomarker for Breast Cancer Prognosis and PARP Inhibitor Therapy

Members of the heterochromatin protein 1 family (HP1α, β and γ) are mostly associated with heterochromatin and play important roles in gene regulation and DNA damage response. Altered expression of individual HP1 subtype has profound impacts on cell proliferation and tumorigenesis. We analyzed the e...

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Podrobná bibliografie
Vydáno v:PLoS One
Hlavní autoři: Lee, Young-Ho, Liu, Xiyong, Qiu, Fuming, O’Connor, Timothy R., Yen, Yun, Ann, David K.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4358987/
https://ncbi.nlm.nih.gov/pubmed/25769025
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0121207
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