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HP1β Is a Biomarker for Breast Cancer Prognosis and PARP Inhibitor Therapy

Members of the heterochromatin protein 1 family (HP1α, β and γ) are mostly associated with heterochromatin and play important roles in gene regulation and DNA damage response. Altered expression of individual HP1 subtype has profound impacts on cell proliferation and tumorigenesis. We analyzed the e...

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Detalhes bibliográficos
Publicado no:PLoS One
Principais autores: Lee, Young-Ho, Liu, Xiyong, Qiu, Fuming, O’Connor, Timothy R., Yen, Yun, Ann, David K.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4358987/
https://ncbi.nlm.nih.gov/pubmed/25769025
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0121207
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