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HP1β Is a Biomarker for Breast Cancer Prognosis and PARP Inhibitor Therapy

Members of the heterochromatin protein 1 family (HP1α, β and γ) are mostly associated with heterochromatin and play important roles in gene regulation and DNA damage response. Altered expression of individual HP1 subtype has profound impacts on cell proliferation and tumorigenesis. We analyzed the e...

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Библиографические подробности
Опубликовано в: :PLoS One
Главные авторы: Lee, Young-Ho, Liu, Xiyong, Qiu, Fuming, O’Connor, Timothy R., Yen, Yun, Ann, David K.
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2015
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4358987/
https://ncbi.nlm.nih.gov/pubmed/25769025
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0121207
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