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Structure-Based Virtual Screening and Discovery of New PPARδ/γ Dual Agonist and PPARδ and γ Agonists

Peroxisome proliferator-activated receptors (PPARs) are involved in the control of carbohydrate and lipid metabolism and are considered important targets to treat diabetes mellitus and metabolic syndrome. The available PPAR ligands have several side effects leading to health risks justifying the sea...

詳細記述

保存先:
書誌詳細
出版年:PLoS One
主要な著者: Maltarollo, Vinicius G., Togashi, Marie, Nascimento, Alessandro S., Honorio, Kathia M.
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4358979/
https://ncbi.nlm.nih.gov/pubmed/25767888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0118790
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