Structure-Based Virtual Screening and Discovery of New PPARδ/γ Dual Agonist and PPARδ and γ Agonists

Peroxisome proliferator-activated receptors (PPARs) are involved in the control of carbohydrate and lipid metabolism and are considered important targets to treat diabetes mellitus and metabolic syndrome. The available PPAR ligands have several side effects leading to health risks justifying the sea...

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Foilsithe in:PLoS One
Main Authors: Maltarollo, Vinicius G., Togashi, Marie, Nascimento, Alessandro S., Honorio, Kathia M.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Public Library of Science 2015
Ábhair:
Research Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4358979/
https://ncbi.nlm.nih.gov/pubmed/25767888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0118790
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