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Intasome architecture and chromatin density modulate retroviral integration into nucleosome
BACKGROUND: Retroviral integration depends on the interaction between intasomes, host chromatin and cellular targeting cofactors as LEDGF/p75 or BET proteins. Previous studies indicated that the retroviral integrase, by itself, may play a role in the local integration site selection within nucleosom...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | Retrovirology |
|---|---|
| Κύριοι συγγραφείς: | , , , , , , , , , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
BioMed Central
2015
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4358916/ https://ncbi.nlm.nih.gov/pubmed/25807893 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12977-015-0145-9 |
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