Intasome architecture and chromatin density modulate retroviral integration into nucleosome

BACKGROUND: Retroviral integration depends on the interaction between intasomes, host chromatin and cellular targeting cofactors as LEDGF/p75 or BET proteins. Previous studies indicated that the retroviral integrase, by itself, may play a role in the local integration site selection within nucleosom...

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Détails bibliographiques
Publié dans:Retrovirology
Auteurs principaux: Benleulmi, Mohamed Salah, Matysiak, Julien, Henriquez, Daniel Rodrigo, Vaillant, Cédric, Lesbats, Paul, Calmels, Christina, Naughtin, Monica, Leon, Oscar, Skalka, Anna Marie, Ruff, Marc, Lavigne, Marc, Andreola, Marie-Line, Parissi, Vincent
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2015
Sujets:
Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4358916/
https://ncbi.nlm.nih.gov/pubmed/25807893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12977-015-0145-9
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