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Declining transition/transversion ratios through time reveal limitations to the accuracy of nucleotide substitution models

BACKGROUND: Genetic analyses of DNA sequences make use of an increasingly complex set of nucleotide substitution models to estimate the divergence between gene sequences. However, there is currently no way to assess the validity of nucleotide substitution models over short time-scales and with limit...

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Bibliografske podrobnosti
izdano v:BMC Evol Biol
Main Authors: Duchêne, Sebastián, Ho, Simon YW, Holmes, Edward C
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4358783/
https://ncbi.nlm.nih.gov/pubmed/25886870
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12862-015-0312-6
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