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Declining transition/transversion ratios through time reveal limitations to the accuracy of nucleotide substitution models

BACKGROUND: Genetic analyses of DNA sequences make use of an increasingly complex set of nucleotide substitution models to estimate the divergence between gene sequences. However, there is currently no way to assess the validity of nucleotide substitution models over short time-scales and with limit...

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書目詳細資料
發表在:BMC Evol Biol
Main Authors: Duchêne, Sebastián, Ho, Simon YW, Holmes, Edward C
格式: Artigo
語言:Inglês
出版: BioMed Central 2015
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4358783/
https://ncbi.nlm.nih.gov/pubmed/25886870
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12862-015-0312-6
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