Reduced Immune Activation during Tenofovir-Emtricitabine Therapy in HIV-negative Individuals

BACKGROUND: Elevated immune activation is associated with an increased risk of HIV acquisition. Tenofovir (TFV) has immunomodulatory properties in vitro, but how this extends in vivo remains unknown. METHODS: HIV-negative adults received daily co-formulated tenofovir-disoproxil-fumarate (TDF) 300 mg...

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Pubblicato in:J Acquir Immune Defic Syndr
Autori principali: Castillo-Mancilla, Jose R., Meditz, Amie, Wilson, Cara, Zheng, Jia-Hua, Palmer, Brent E., Lee, Eric J., Gardner, Edward M., Seifert, Sharon, Kerr, Becky, Bushman, Lane R., MaWhinney, Samantha, Anderson, Peter L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2015
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4358752/
https://ncbi.nlm.nih.gov/pubmed/25763783
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/QAI.0000000000000529
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