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Peptide-enhanced mRNA transfection in cultured mouse cardiac fibroblasts and direct reprogramming towards cardiomyocyte-like cells

The treatment of myocardial infarction is a major challenge in medicine due to the inability of heart tissue to regenerate. Direct reprogramming of endogenous cardiac fibroblasts into functional cardiomyocytes via the delivery of transcription factor mRNAs has the potential to regenerate cardiac tis...

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Podrobná bibliografie
Vydáno v:Int J Nanomedicine
Hlavní autoři: Lee, Kunwoo, Yu, Pengzhi, Lingampalli, Nithya, Kim, Hyun Jin, Tang, Richard, Murthy, Niren
Médium: Artigo
Jazyk:Inglês
Vydáno: Dove Medical Press 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4358644/
https://ncbi.nlm.nih.gov/pubmed/25834424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S75124
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