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Direct reprogramming of fibroblasts into cardiomyocytes

Cardiovascular diseases are the leading causes of death in the world. The limited regenerative capacity of adult cardiomyocytes is the major barrier for heart regeneration. After myocardial infarction, myofibroblasts are the dominant cell type in the infarct zone. Therefore, it is a good idea to rep...

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Bibliographic Details
Published in:Stem Cell Res Ther
Main Authors: Chen, Yueqiu, Yang, Ziying, Zhao, Zhen-Ao, Shen, Zhenya
Format: Artigo
Language:Inglês
Published: BioMed Central 2017
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5445304/
https://ncbi.nlm.nih.gov/pubmed/28545505
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-017-0569-3
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