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Peptide-enhanced mRNA transfection in cultured mouse cardiac fibroblasts and direct reprogramming towards cardiomyocyte-like cells

The treatment of myocardial infarction is a major challenge in medicine due to the inability of heart tissue to regenerate. Direct reprogramming of endogenous cardiac fibroblasts into functional cardiomyocytes via the delivery of transcription factor mRNAs has the potential to regenerate cardiac tis...

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Detalhes bibliográficos
Publicado no:Int J Nanomedicine
Main Authors: Lee, Kunwoo, Yu, Pengzhi, Lingampalli, Nithya, Kim, Hyun Jin, Tang, Richard, Murthy, Niren
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4358644/
https://ncbi.nlm.nih.gov/pubmed/25834424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S75124
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