A genome-scale in vivo loss-of-function screen identifies Phf6 as a lineage-specific regulator of leukemia cell growth

We performed a genome-scale shRNA screen for modulators of B-cell leukemia progression in vivo. Results from this work revealed dramatic distinctions between the relative effects of shRNAs on the growth of tumor cells in culture versus in their native microenvironment. Specifically, we identified ma...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Genes Dev
Päätekijät: Meacham, Corbin E., Lawton, Lee N., Soto-Feliciano, Yadira M., Pritchard, Justin R., Joughin, Brian A., Ehrenberger, Tobias, Fenouille, Nina, Zuber, Johannes, Williams, Richard T., Young, Richard A., Hemann, Michael T.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Cold Spring Harbor Laboratory Press 2015
Aiheet:
Research Communication
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4358400/
https://ncbi.nlm.nih.gov/pubmed/25737277
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.254151.114
Tagit: Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!

Samankaltaisia teoksia