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Identification of ‘erasers’ for lysine crotonylated histone marks using a chemical proteomics approach

Posttranslational modifications (PTMs) play a crucial role in a wide range of biological processes. Lysine crotonylation (Kcr) is a newly discovered histone PTM that is enriched at active gene promoters and potential enhancers in mammalian cell genomes. However, the cellular enzymes that regulate th...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:eLife
Hauptverfasser: Bao, Xiucong, Wang, Yi, Li, Xin, Li, Xiao-Meng, Liu, Zheng, Yang, Tangpo, Wong, Chi Fat, Zhang, Jiangwen, Hao, Quan, Li, Xiang David
Format: Artigo
Sprache:Inglês
Veröffentlicht: eLife Sciences Publications, Ltd 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4358366/
https://ncbi.nlm.nih.gov/pubmed/25369635
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.02999
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