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Developing diazirine-based chemical probes to identify histone modification ‘readers’ and ‘erasers’
Post translational modifications (PTMs, e.g., phosphorylation, acetylation and methylation) of histone play important roles in regulating many fundamental cellular processes such as gene transcription, DNA replication and damage repair. While ‘writer’ and ‘eraser’ enzymes modify histones by catalyzi...
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| Publié dans: | Chem Sci |
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| Auteurs principaux: | , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Royal Society of Chemistry
2015
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5811097/ https://ncbi.nlm.nih.gov/pubmed/29560188 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c4sc02328e |
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