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Structural Basis of Plant Homeodomain Finger 6 (PHF6) Recognition by the Retinoblastoma Binding Protein 4 (RBBP4) Component of the Nucleosome Remodeling and Deacetylase (NuRD) Complex

The NuRD complex is a conserved transcriptional coregulator that contains both chromatin-remodeling and histone deacetylase activities. Mutations of PHF6 are found in patients with Börjeson-Forssman-Lehmann syndrome, T-cell acute lymphoblastic leukemia, or acute myeloid leukemia. Recently, PHF6 was...

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Enregistré dans:
Détails bibliographiques
Publié dans:J Biol Chem
Auteurs principaux: Liu, Zhonghua, Li, Fudong, Zhang, Beibei, Li, Sai, Wu, Jihui, Shi, Yunyu
Format: Artigo
Langue:Inglês
Publié: American Society for Biochemistry and Molecular Biology 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4358295/
https://ncbi.nlm.nih.gov/pubmed/25601084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.610196
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