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Anoctamin-6 Controls Bone Mineralization by Activating the Calcium Transporter NCX1
Anoctamin-6 (Ano6, TMEM16F) belongs to a family of putative Ca(2+)-activated Cl(−) channels and operates as membrane phospholipid scramblase. Deletion of Ano6 leads to reduced skeleton size, skeletal deformities, and mineralization defects in mice. However, it remains entirely unclear how a lack of...
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| Publicado en: | J Biol Chem |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Society for Biochemistry and Molecular Biology
2015
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4358264/ https://ncbi.nlm.nih.gov/pubmed/25589784 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.602979 |
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