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Anoctamin-6 Controls Bone Mineralization by Activating the Calcium Transporter NCX1
Anoctamin-6 (Ano6, TMEM16F) belongs to a family of putative Ca(2+)-activated Cl(−) channels and operates as membrane phospholipid scramblase. Deletion of Ano6 leads to reduced skeleton size, skeletal deformities, and mineralization defects in mice. However, it remains entirely unclear how a lack of...
Wedi'i Gadw mewn:
| Cyhoeddwyd yn: | J Biol Chem |
|---|---|
| Prif Awduron: | , , , , , |
| Fformat: | Artigo |
| Iaith: | Inglês |
| Cyhoeddwyd: |
American Society for Biochemistry and Molecular Biology
2015
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| Pynciau: | |
| Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4358264/ https://ncbi.nlm.nih.gov/pubmed/25589784 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.602979 |
| Tagiau: |
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