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Conophylline Protects Cells in Cellular Models of Neurodegenerative Diseases by Inducing Mammalian Target of Rapamycin (mTOR)-independent Autophagy

Macroautophagy is a cellular response that leads to the bulk, nonspecific degradation of cytosolic components, including organelles. In recent years, it has been recognized that autophagy is essential for prevention of neurodegenerative diseases, including Parkinson disease (PD) and Huntington disea...

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Detalles Bibliográficos
Publicado en:J Biol Chem
Main Authors: Sasazawa, Yukiko, Sato, Natsumi, Umezawa, Kazuo, Simizu, Siro
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2015
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4358256/
https://ncbi.nlm.nih.gov/pubmed/25596530
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.606293
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