The BRCA1 Tumor Suppressor Binds to Inositol 1,4,5-Trisphosphate Receptors to Stimulate Apoptotic Calcium Release

The inositol 1,4,5-trisphosphate receptor (IP(3)R) is a ubiquitously expressed endoplasmic reticulum (ER)-resident calcium channel. Calcium release mediated by IP(3)Rs influences many signaling pathways, including those regulating apoptosis. IP(3)R activity is regulated by protein-protein interactio...

詳細記述

保存先:
書誌詳細
出版年:J Biol Chem
主要な著者: Hedgepeth, Serena C., Garcia, M. Iveth, Wagner, Larry E., Rodriguez, Ana M., Chintapalli, Sree V., Snyder, Russell R., Hankins, Gary D. V., Henderson, Beric R., Brodie, Kirsty M., Yule, David I., van Rossum, Damian B., Boehning, Darren
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Biochemistry and Molecular Biology 2015
主題:
Signal Transduction
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4358148/
https://ncbi.nlm.nih.gov/pubmed/25645916
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.611186
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