A tumor suppressor locus within 3p14-p12 mediates rapid cell death of renal cell carcinoma in vivo.

High frequency loss of alleles and cytogenetic aberrations on the short arm of chromosome 3 have been documented in renal cell carcinoma (RCC). Potentially, three distinct regions on 3p could encode tumor suppressor genes involved in the genesis of this cancer. We report that the introduction of a c...

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Bibliographic Details
Main Authors: Sanchez, Y, el-Naggar, A, Pathak, S, Killary, A M
Format: Artigo
Language:Inglês
Published: 1994
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC43581/
https://ncbi.nlm.nih.gov/pubmed/8159756
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