Mechanisms Mediating Enhanced Neutralization Efficacy of Staphylococcal Enterotoxin B by Combinations of Monoclonal Antibodies

Staphylococcal enterotoxin B (SEB) is a superantigen that cross-links the major histocompatibility complex class II and specific V-β chains of the T-cell receptor, thus forming a ternary complex. Developing neutralizing mAb to disrupt the ternary complex and abrogate the resulting toxicity is a majo...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:J Biol Chem
Main Authors: Dutta, Kaushik, Varshney, Avanish K., Franklin, Matthew C., Goger, Michael, Wang, Xiaobo, Fries, Bettina C.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2015
Fag:
Immunology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4358096/
https://ncbi.nlm.nih.gov/pubmed/25572397
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.630715
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker