Generation, Characterization, and Epitope Mapping of Neutralizing and Protective Monoclonal Antibodies against Staphylococcal Enterotoxin B-induced Lethal Shock

T-cell stimulating activity of Staphylococcal enterotoxin B (SEB) is an important factor in the pathogenesis of certain staphylococcal diseases including SEB mediated shock. SEB is one of the most potent superantigens known and treatment of SEB induced shock remains a challenge. We generated and cha...

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Detalhes bibliográficos
Main Authors: Varshney, Avanish K., Wang, Xiaobo, Cook, Emily, Dutta, Kaushik, Scharff, Matthew D., Goger, Michael J., Fries, Bettina C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3059042/
https://ncbi.nlm.nih.gov/pubmed/21233204
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.212407
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