Targeted Disruption of Glycogen Synthase Kinase 3a (Gsk3a) in Mice Affects Sperm Motility Resulting in Male Infertility

The signaling enzyme glycogen synthase kinase 3 (GSK3) exists as two isoforms—GSK3A and GSK3B. Protein phosphorylation by GSK3 has important signaling roles in several cells. In our past work, we found that both isoforms of GSK3 are present in mouse sperm and that catalytic GSK3 activity correlates...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Biol Reprod
Main Authors: Bhattacharjee, Rahul, Goswami, Suranjana, Dudiki, Tejasvi, Popkie, Anthony P., Phiel, Christopher J., Kline, Douglas, Vijayaraghavan, Srinivasan
Format: Artigo
Jezik:Inglês
Izdano: Society for the Study of Reproduction, Inc. 2015
Teme:
Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4358024/
https://ncbi.nlm.nih.gov/pubmed/25568307
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1095/biolreprod.114.124495
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