Targeted Disruption of Glycogen Synthase Kinase 3a (Gsk3a) in Mice Affects Sperm Motility Resulting in Male Infertility

The signaling enzyme glycogen synthase kinase 3 (GSK3) exists as two isoforms—GSK3A and GSK3B. Protein phosphorylation by GSK3 has important signaling roles in several cells. In our past work, we found that both isoforms of GSK3 are present in mouse sperm and that catalytic GSK3 activity correlates...

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Bibliographische Detailangaben
Veröffentlicht in:Biol Reprod
Hauptverfasser: Bhattacharjee, Rahul, Goswami, Suranjana, Dudiki, Tejasvi, Popkie, Anthony P., Phiel, Christopher J., Kline, Douglas, Vijayaraghavan, Srinivasan
Format: Artigo
Sprache:Inglês
Veröffentlicht: Society for the Study of Reproduction, Inc. 2015
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Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4358024/
https://ncbi.nlm.nih.gov/pubmed/25568307
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1095/biolreprod.114.124495
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