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TEFM is a potent stimulator of mitochondrial transcription elongation in vitro

A single-subunit RNA polymerase, POLRMT, transcribes the mitochondrial genome in human cells. Recently, a factor termed as the mitochondrial transcription elongation factor, TEFM, was shown to stimulate transcription elongation in vivo, but its effect in vitro was relatively modest. In the current w...

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Bibliografske podrobnosti
izdano v:Nucleic Acids Res
Main Authors: Posse, Viktor, Shahzad, Saba, Falkenberg, Maria, Hällberg, B. Martin, Gustafsson, Claes M.
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4357710/
https://ncbi.nlm.nih.gov/pubmed/25690892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv105
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