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Mitochondrial transcription termination factor 1 directs polar replication fork pausing

During replication of nuclear ribosomal DNA (rDNA), clashes with the transcription apparatus can cause replication fork collapse and genomic instability. To avoid this problem, a replication fork barrier protein is situated downstream of rDNA, there preventing replication in the direction opposite r...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Shi, Yonghong, Posse, Viktor, Zhu, Xuefeng, Hyvärinen, Anne K., Jacobs, Howard T., Falkenberg, Maria, Gustafsson, Claes M.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4937320/
https://ncbi.nlm.nih.gov/pubmed/27112570
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw302
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