Identification of a second GTP-bound magnesium ion in archaeal initiation factor 2

Eukaryotic and archaeal translation initiation processes involve a heterotrimeric GTPase e/aIF2 crucial for accuracy of start codon selection. In eukaryotes, the GTPase activity of eIF2 is assisted by a GTPase-activating protein (GAP), eIF5. In archaea, orthologs of eIF5 are not found and aIF2 GTPas...

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Detalles Bibliográficos
Publicado en:Nucleic Acids Res
Autores principales: Dubiez, Etienne, Aleksandrov, Alexey, Lazennec-Schurdevin, Christine, Mechulam, Yves, Schmitt, Emmanuelle
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2015
Materias:
Structural Biology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4357699/
https://ncbi.nlm.nih.gov/pubmed/25690901
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv053
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