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Polysome arrest restricts miRNA turnover by preventing exosomal export of miRNA in growth-retarded mammalian cells

MicroRNAs (miRNAs) are tiny posttranscriptional regulators of gene expression in metazoan cells, where activity and abundance of miRNAs are tightly controlled. Regulated turnover of these regulatory RNAs is important to optimize cellular response to external stimuli. We report that the stability of...

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Detaylı Bibliyografya
Yayımlandı:Mol Biol Cell
Asıl Yazarlar: Ghosh, Souvik, Bose, Mainak, Ray, Anirban, Bhattacharyya, Suvendra N.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: The American Society for Cell Biology 2015
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4357507/
https://ncbi.nlm.nih.gov/pubmed/25609084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E14-11-1521
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