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Involvement of general control nonderepressible kinase 2 in cancer cell apoptosis by posttranslational mechanisms
General control nonderepressible kinase 2 (GCN2) is a promising target for cancer therapy. However, the role of GCN2 in cancer cell survival or death is elusive; further, small molecules targeting GCN2 signaling are not available. By using a GCN2 level-based drug screening assay, we found that GCN2...
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| Publicat a: | Mol Biol Cell |
|---|---|
| Autors principals: | , , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
The American Society for Cell Biology
2015
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4357505/ https://ncbi.nlm.nih.gov/pubmed/25589675 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E14-10-1438 |
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