The general control nonderepressible-2 kinase mediates stress response and longevity induced by target of rapamycin inactivation in Caenorhabditis elegans

The general control nonderepressible 2 (GCN2) kinase is a nutrient-sensing pathway that responds to amino acids deficiency and induces a genetic program to effectively maintain cellular homeostasis. Here we established the conserved role of Caenorhabditis elegans GCN-2 under amino acid limitation as...

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Bibliographic Details
Published in:Aging Cell
Main Authors: Rousakis, Aris, Vlassis, Arsenios, Vlanti, Anna, Patera, Stefania, Thireos, George, Syntichaki, Popi
Format: Artigo
Language:Inglês
Published: BlackWell Publishing Ltd 2013
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Original Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4225475/
https://ncbi.nlm.nih.gov/pubmed/23692540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12101
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