تحميل...
Impaired Systemic Tetrahydrobiopterin Bioavailability and Increased Dihydrobiopterin in Adult Falciparum Malaria: Association with Disease Severity, Impaired Microvascular Function and Increased Endothelial Activation
Tetrahydrobiopterin (BH(4)) is a co-factor required for catalytic activity of nitric oxide synthase (NOS) and amino acid-monooxygenases, including phenylalanine hydroxylase. BH(4) is unstable: during oxidative stress it is non-enzymatically oxidized to dihydrobiopterin (BH(2)), which inhibits NOS. D...
محفوظ في:
| الحاوية / القاعدة: | PLoS Pathog |
|---|---|
| المؤلفون الرئيسيون: | , , , , , , , , |
| التنسيق: | Artigo |
| اللغة: | Inglês |
| منشور في: |
Public Library of Science
2015
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| الموضوعات: | |
| الوصول للمادة أونلاين: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4357386/ https://ncbi.nlm.nih.gov/pubmed/25764397 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1004667 |
| الوسوم: |
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