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Phospholamban phosphorylation, mutation, and structural dynamics: a biophysical approach to understanding and treating cardiomyopathy

We review the recent development of novel biochemical and spectroscopic methods to determine the site-specific phosphorylation, expression, mutation, and structural dynamics of phospholamban (PLB), in relation to its function (inhibition of the cardiac calcium pump, SERCA2a), with specific focus on...

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Detalles Bibliográficos
Publicado en:Biophys Rev
Autores principales: Ablorh, Naa-Adjeley D., Thomas, David D.
Formato: Artigo
Lenguaje:Inglês
Publicado: Springer Berlin Heidelberg 2015
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4356992/
https://ncbi.nlm.nih.gov/pubmed/28509982
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12551-014-0157-z
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