Synthetic Phosphopeptides Enable Quantitation of the Content and Function of the Four Phosphorylation States of Phospholamban in Cardiac Muscle

We have studied the differential effects of phospholamban (PLB) phosphorylation states on the activity of the sarcoplasmic reticulum Ca-ATPase (SERCA). It has been shown that unphosphorylated PLB (U-PLB) inhibits SERCA and that phosphorylation of PLB at Ser-16 or Thr-17 relieves this inhibition in c...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Ablorh, Naa-Adjeley D., Dong, Xiaoqiong, James, Zachary M., Xiong, Qiang, Zhang, Jianyi, Thomas, David D., Karim, Christine B.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Biochemistry and Molecular Biology 2014
Pynciau:
Enzymology
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4200288/
https://ncbi.nlm.nih.gov/pubmed/25190804
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.556621
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