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Synthetic Phosphopeptides Enable Quantitation of the Content and Function of the Four Phosphorylation States of Phospholamban in Cardiac Muscle

We have studied the differential effects of phospholamban (PLB) phosphorylation states on the activity of the sarcoplasmic reticulum Ca-ATPase (SERCA). It has been shown that unphosphorylated PLB (U-PLB) inhibits SERCA and that phosphorylation of PLB at Ser-16 or Thr-17 relieves this inhibition in c...

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書誌詳細
主要な著者: Ablorh, Naa-Adjeley D., Dong, Xiaoqiong, James, Zachary M., Xiong, Qiang, Zhang, Jianyi, Thomas, David D., Karim, Christine B.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Biochemistry and Molecular Biology 2014
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オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4200288/
https://ncbi.nlm.nih.gov/pubmed/25190804
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.556621
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