IQGAP1 regulates actin cytoskeleton organization in podocytes through interaction with nephrin

Increasing data has shown that the cytoskeletal reorganization of podocytes is involved in the onset of proteinuria and the progression of glomerular disease. Nephrin behaves as a signal sensor of the slit diaphragm to transmit cytoskeletal signals to maintain the unique structure of podocytes. Howe...

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Udgivet i:Cell Signal
Main Authors: Liu, Yipeng, Liang, Wei, Yang, Yingjie, Pan, Yangbin, Yang, Qian, Chen, Xinghua, Singhal, Pravin C., Ding, Guohua
Format: Artigo
Sprog:Inglês
Udgivet: 2015
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4356988/
https://ncbi.nlm.nih.gov/pubmed/25652011
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellsig.2015.01.015
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