Angiotensin II down-regulates nephrin–Akt signaling and induces podocyte injury: roleof c-Abl

Recent studies have shown that nephrin plays a vital role in angiotensin II (Ang II)–induced podocyte injury and thus contributes to the onset of proteinuria and the progression of renal diseases, but its specific mechanism remains unclear. c-Abl is an SH2/SH3 domain–containing nonreceptor tyrosine...

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Publicat a:Mol Biol Cell
Autors principals: Yang, Qian, Ma, Yiqiong, Liu, Yipeng, Liang, Wei, Chen, Xinghua, Ren, Zhilong, Wang, Huiming, Singhal, Pravin C., Ding, Guohua
Format: Artigo
Idioma:Inglês
Publicat: The American Society for Cell Biology 2016
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Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4694757/
https://ncbi.nlm.nih.gov/pubmed/26510503
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E15-04-0223
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