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Angiotensin II down-regulates nephrin–Akt signaling and induces podocyte injury: roleof c-Abl
Recent studies have shown that nephrin plays a vital role in angiotensin II (Ang II)–induced podocyte injury and thus contributes to the onset of proteinuria and the progression of renal diseases, but its specific mechanism remains unclear. c-Abl is an SH2/SH3 domain–containing nonreceptor tyrosine...
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| Veröffentlicht in: | Mol Biol Cell |
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| Hauptverfasser: | , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
The American Society for Cell Biology
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4694757/ https://ncbi.nlm.nih.gov/pubmed/26510503 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E15-04-0223 |
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