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Kirenol Attenuates Experimental Autoimmune Encephalomyelitis by Inhibiting Differentiation of Th1 and Th17 Cells and Inducing Apoptosis of Effector T Cells

Experimental autoimmune encephalomyelitis (EAE), a model of multiple sclerosis (MS), is characterized by CNS demyelination mediated by autoreactive T cells. Kirenol, a biologically active substance isolated from Herba Siegesbeckiae, has potent anti-inflammatory activities. Here we investigated effec...

詳細記述

保存先:
書誌詳細
出版年:Sci Rep
主要な著者: Xiao, Juan, Yang, Rongbing, Yang, Lin, Fan, Xiaohang, Liu, Wenwei, Deng, Wenbin
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4356981/
https://ncbi.nlm.nih.gov/pubmed/25762107
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep09022
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