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Deficiency of Thrombonspondin-1 Reduces Th17 Differentiation and Attenuates Experimental Autoimmune Encephalomyelitis
Transforming growth factor β (TGF-β) plays a role both in the induction of Treg and in the differentiation of the IL-17-secreting T cells (Th17) which drive inflammation in experimental autoimmune encephalomyelitis (EAE). We investigated the role that thrombospondin-1 (TSP-1) dependent activation of...
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| Principais autores: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2735759/ https://ncbi.nlm.nih.gov/pubmed/19181483 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaut.2008.12.004 |
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