Epoxy-α-Lapachone Has In Vitro and In Vivo Anti-Leishmania (Leishmania) amazonensis Effects and Inhibits Serine Proteinase Activity in This Parasite

Leishmania (Leishmania) amazonensis is a protozoan that causes infections with a broad spectrum of clinical manifestations. The currently available chemotherapeutic treatments present many problems, such as several adverse side effects and the development of resistant strains. Natural compounds have...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Souza-Silva, Franklin, Bourguignon, Saulo Cabral, Pereira, Bernardo Acácio Santini, Côrtes, Luzia Monteiro de Castro, de Oliveira, Luiz Filipe Gonçalves, Henriques-Pons, Andrea, Finkelstein, Lea Cysne, Ferreira, Vitor Francisco, Carneiro, Paula Fernandes, de Pinho, Rosa Teixeira, Caffarena, Ernesto Raul, Alves, Carlos Roberto
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2015
Assuntos:
Biologic Response Modifiers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4356828/
https://ncbi.nlm.nih.gov/pubmed/25583728
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.04742-14
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