Bis-Benzimidazole Hits against Naegleria fowleri Discovered with New High-Throughput Screens

Naegleria fowleri is a pathogenic free-living amoeba (FLA) that causes an acute fatal disease known as primary amoebic meningoencephalitis (PAM). The major problem for infections with any pathogenic FLA is a lack of effective therapeutics, since PAM has a case mortality rate approaching 99%. Clearly...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Antimicrob Agents Chemother
Prif Awduron: Rice, Christopher A., Colon, Beatrice L., Alp, Mehmet, Göker, Hakan, Boykin, David W., Kyle, Dennis E.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Microbiology 2015
Pynciau:
Experimental Therapeutics
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4356813/
https://ncbi.nlm.nih.gov/pubmed/25605363
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.05122-14
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