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Novel Approach To Optimize Synergistic Carbapenem-Aminoglycoside Combinations against Carbapenem-Resistant Acinetobacter baumannii

Acinetobacter baumannii is among the most dangerous pathogens and emergence of resistance is highly problematic. Our objective was to identify and rationally optimize β-lactam-plus-aminoglycoside combinations via novel mechanism-based modeling that synergistically kill and prevent resistance of carb...

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Bibliografiska uppgifter
I publikationen:Antimicrob Agents Chemother
Huvudupphovsmän: Yadav, Rajbharan, Landersdorfer, Cornelia B., Nation, Roger L., Boyce, John D., Bulitta, Jürgen B.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology 2015
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4356774/
https://ncbi.nlm.nih.gov/pubmed/25645842
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.04379-14
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