Aminoglycoside Concentrations Required for Synergy with Carbapenems against Pseudomonas aeruginosa Determined via Mechanistic Studies and Modeling

This study aimed to systematically identify the aminoglycoside concentrations required for synergy with a carbapenem and characterize the permeabilizing effect of aminoglycosides on the outer membrane of Pseudomonas aeruginosa. Monotherapies and combinations of four aminoglycosides and three carbape...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Antimicrob Agents Chemother
Prif Awduron: Yadav, Rajbharan, Bulitta, Jürgen B., Schneider, Elena K., Shin, Beom Soo, Velkov, Tony, Nation, Roger L., Landersdorfer, Cornelia B.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Microbiology 2017
Pynciau:
Pharmacology
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5700360/
https://ncbi.nlm.nih.gov/pubmed/28893782
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00722-17
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