Enhanced oral bioavailability of fenofibrate using polymeric nanoparticulated systems: physicochemical characterization and in vivo investigation

BACKGROUND: The intention of this research was to prepare and compare various solubility-enhancing nanoparticulated systems in order to select a nanoparticulated formulation with the most improved oral bioavailability of poorly water-soluble fenofibrate. METHODS: The most appropriate excipients for...

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Bibliographische Detailangaben
Veröffentlicht in:Int J Nanomedicine
Hauptverfasser: Yousaf, Abid Mehmood, Kim, Dong Wuk, Oh, Yu-Kyoung, Yong, Chul Soon, Kim, Jong Oh, Choi, Han-Gon
Format: Artigo
Sprache:Inglês
Veröffentlicht: Dove Medical Press 2015
Schlagworte:
Original Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4356686/
https://ncbi.nlm.nih.gov/pubmed/25784807
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S78895
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